Primatropin – Ozempic

WHY CHOOSE SEMAGLUTIDE– PRIMATROPIN

How Semaglutide Causes Improved Blood Sugar and Weight Loss
Semaglutide was originally developed to improve glycemic control in adults with Type 2 Diabetes and later was approved for weight management because of its efficacy in this area. But how does it work?
When you have Type 2 Diabetes, your pancreas doesn’t produce enough insulin,4 a hormone that regulates blood glucose levels. GLP-1 is another hormone that stimulates your pancreas to release insulin. Since all forms of Semaglutide and Compounded Semaglutide are GLP-1 receptor agonists, they act like GLP-1 by binding to your body’s GLP-1 receptor, effectively increasing insulin production. This helps you to keep your blood sugar levels within a healthy range.5
Beyond its primary use, Semaglutide and Compounded Semaglutide have also been shown to:6
• Reduce appetite and hunger
• Increase feelings of fullness
• Reduce food cravings and energy intake
• Delay gastric emptying (when food leaves the stomach and goes into the intestines)
All these effects reduce calorie intake, leading to weight loss.
Potential Risks
While it has many benefits, there are some side effects associated with Semaglutide and Compounded Semaglutide, including:7
• Nausea
• V omiting
• Abdominal pain
• Constipation
• Severe gastrointestinal reactions
• Hypoglycemia
• Pancreatitis
• Acute kidney injury
They may also cause injection site reactions or reduced absorption of other oral medications due to delayed gastric emptying.7 It’s important to note that balance is key when taking either type of Semaglutide. Its efficacy and the severity of adverse effects depend on the right dosage.
How to Administer Injectable Semaglutide and Compounded Semaglutide
Semaglutide and Compounded Semaglutide are administered as a once-weekly subcutaneous injection in the abdomen, upper arm, or thigh at any time of the day. If you choose to inject it into the same area each week, you should use a different injection site.7
Semaglutide is delivered in a dry 1mg vial that must be mixed with bacteriostatic water. Using a 0.5ml insulin syringe, draw 40 units and inject into the 1mg vial. Allow to sit for 2 minutes. Do not shake the vial. Once mixed, your vial should be stored in a cold, dry place (a refrigerator ideally). You can take it with or without meals.
Recipients of Compounded Semaglutide will receive the injectable medication as a vial and syringe. Because of this, you must pay close attention to filling the syringe with the correct dosing amount when administering it.
If you also inject insulin, you can administer both in the same body region as long as you meet three criteria:7
1. Don’t inject them side by side
2. Never mix the two together
3. Don’t inject them at the same time
If you miss a dose, administer the shot as soon as you can, no later than five days after the missed day. If you exceed five days, skip the missed dose and administer it on your next scheduled day. Then, go back to your regular injection schedule.
Starting Dose
The recommended starting dosage of Semaglutide or Compounded Semaglutide is 0.25 mg weekly for the first month (10 units on the syringe). This amount is just meant to introduce the medication into your system so it can begin acclimation. It doesn’t start regulating your blood sugar levels at this point.7
Gradual Increments
After the first four weeks, your provider will advise when to increase the dosage to 0.5 mg once a week for the next month (20 units on the syringe). At this point, the medication begins regulating blood sugar levels.7
After at least four weeks on a 0.5 mg dose, your provider may increase your weekly dose up to the maximum recommended dosage of 1.0 mg (40 units on the syringe), if you need additional glycemic control. This is the maximum recommended amount for maintenance treatment.
Factors Influencing Dosage
Several factors influence your starting and maintenance dosage of Semaglutide, including:
• Disease: Having certain diseases reduces the excretion and absorption of medications.
• Genetics: Certain genetic factors such as body mass and build can affect medication
distribution throughout the body.

• Age: Effects of aging, such as impaired kidney function, can reduce excretion and increase toxic response (when your body can’t get the medication out of the bloodstream).
• Nutritional status: Previous and current food and drug experiences can affect how your body metabolizes Semaglutide.
• Sex: Your biological sex affects your body’s metabolism of the medication.
• Hormonal status (i.e., pregnancy): Maternal toxicity can negatively affect the fetus.
• Circadian rhythm: Administering medications at the wrong time of day can cause the
doses to elicit a toxic response.
All these factors influence how medications affect your system, how it processes them, and the severity of the side effects.10 That’s why there’s no blanket approach to starting dosages and progressions. Each dosing plan is unique to each person’s health situation and medical history.